Alzheimer’s Disease Small Molecule Compound Kit-1 KBAD-1
English name:Alzheimer’s Disease Small Molecule Compound Kit-1
Specification:8*1mL(10mM) ; 8*2mg ; 8*5mg
Storage conditions:Store at -20℃
Shipping conditions:Freeze transportation
Product Introduction
| CAS number | Product number | Product name | Molecular formula | molecular weight | Corresponding target | Product Description |
| 22427-39-0 | IG0240 | Ginsenoside Rg1; Ginsenoside Rg1 | C42H72O14 | 801.01 | Amyloid-β | Works by reducing brain Aβ levels. |
| 52286-59-6 | IG0650 | Ginsenoside Re; Ginsenoside Re | C48H82O18 | 947.15 | Amyloid-β | Ginsenoside Re can reduce β-amyloid (Aβ) and inhibit JNK and NF-κB. |
| 80418-24-2 | IN0240 | Notoginsenoside R1; Notoginsenoside R1 | C47H80O18 | 933.13 | Amyloid-β；TNF-α | It is the main bioactive component in Panax notoginseng and is reported to have certain neuronal protective effects. It has a protective effect on the APP/PS1 mouse model of Alzheimer's disease by inhibiting Aβ accumulation. |
| 20736-08-7 | IS0520 | Saikosaponin C; Saikosaponin C | C 48 H 78 O 17 | 927.12 | Amyloid-β；tau protein | It is the active ingredient in Bupleurum, and it mainly targets amyloid beta and tau Proteins in Alzheimer's disease. |
| 134308-13-7 | IT2230 | Tolcapone; Tolcapone | C 14 H 11 NO 5 | 273.24 | Aβ42 | Is a potent inhibitor of Aβ42 oligomerization and fibril formation |
| 97657-92-6 | IL0790 | Latrepirdine 2HCl | C21H25N3·2HCl | 392.37 | Amyloid-β | Stimulates amyloid precursor protein (APP) catabolism and beta-amyloid (amyloid-β, Aβ) secretion. |
| 425386-60-3 | IS1540 | Semagacestat; Semagacet | C 19 H 27 N 3 O 4 | 361.44 | Amyloid β；γ-secretase | Is a γ-secretase inhibitor that inhibits β-amyloid (Aβ42), Aβ38 and Aβ40. Can be used in research related to Alzheimer's disease. |
| 58749-23-8 | IL2000 | Licochalcone B; Licochalcone B | C16H14O5 | 286.28 | Amyloid β | Inhibits amyloid β (Aβ420) self-aggregation and disintegrates preformed Aβ42 fibrils, reducing metal-induced Aβ42 aggregation by chelating metal ions. |
This set selects several compounds targeting Amyloid-β, which can be used in Alzheimer's disease-related research and facilitate customers' preliminary screening and other operations. Customers can also flexibly customize exclusive Kits according to their own needs. | ||||||
Things to note
Considerations
1. This product is for scientific research use only. Do not use it for medicine, clinical diagnosis or treatment, food and cosmetics, etc. Do not store in ordinary residential areas.
2. For your safety and health, please wear a lab coat, disposable gloves and a mask.
3. The experimental results can be affected by many factors. The relevant processing is limited to the product itself and does not involve other compensation.
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