Hypoxia Small Molecule Compound Kit-2 KBHIF-2
Name：Hypoxia Small Molecule Compound Kit-2
Specification： 10*1mL(10mM) ; 10*2mg ; 10*5mg
Storage conditions：Store at -20℃
Shipping conditions：Freeze transportation
Product Introduction
| CAS number | Product number | Product name | Molecular formula | molecular weight | Corresponding target | Product Description |
| 23180-57-6 | KB0030 | Paeoniflorin; paeoniflorin | C23H28O11 | 480.46 | HIF/HIF Prolyl-Hydroxylase | It has been reported that paeoniflorin can inhibit HIF-1α through the mTOR-dependent pathway. |
| 89464-63-1 | KB0540 | DMOG; dimethyloxamidoacetic acid | C 6 H 9 NO 5 | 175.14 | HIF/HIF Prolyl-Hydroxylase | It is a competitive inhibitor of HIF-1α prolyl hydroxylase (HIF-PH). |
| 5302-45-4 | KB0320 | β-n-Oxalylamino-l-alanine; notoginseng | C 5 H 8 N 2 O 5 | 176.13 | HIF/HIF Prolyl-Hydroxylase | Is a HIF-prolyl hydroxylase-2 (PHD-2) inhibitor |
| 874590-32-6 | KB5850 | M1001 | C 1 7 H 1 7 N 3 O 2 S | 327.4 | HIF-2α | M1001 is a weak HIF-2α agonist that binds to the HIF-2α PAS-B domain. |
| 38520-57-9 | KB4520 | N-Acetylcysteine Amide; N-acetyl-L-cystine | C5H10N2O2S | 162.21 | HIF-1α | It is an antioxidant with anti-inflammatory activity and can regulate the activation of NF-κB, HIF-1α and ROS. |
| 53123-88-9 | KB0010 | Rapamycin; rapamycin | C 51 H 79 NO 13 | 914.18 | mTOR | Is a potent and specific mTOR inhibitor and autophagy activator. |
| 38748-32-2 | KB0310 | Triptolide; triptolide | C20H24O6 | 360.4 | NF-κB | Is an inhibitor of NF-κB activation. |
| 284461-73-0 | KB0220 | Sorafenib; Sorafenib | C 21 H 16 ClF 3 N 4 O 3 | 464.83 | Raf | It is a multiple kinase inhibitor of Raf-1 and B-Raf, and can also inhibit VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT. |
| 117-39-5 | KB0010 | Quercetin; Quercetin | C 15 H 10 W 7 | 302.24 | PI3K | Is a Sirt1 activator and also a PI3K inhibitor |
| 35825-57-1 | KB0590 | Cryptotanshinone; cryptotanshinone | C 19 H 20 O 3 | 296.36 | STAT | Is a STAT3 inhibitor |
This set selects several compounds commonly used in research related to cellular oxygen sensing to facilitate customers' preliminary screening and other operations. Customers can also flexibly customize exclusive Kits according to their own needs.
2. 靶向HIF/HIF Prolyl-Hydroxylase、mTOR、NF-κB、Raf、PI3K、STAT | ||||||
Things to note
Considerations
1. This product is for scientific research use only. Do not use it for medicine, clinical diagnosis or treatment, food and cosmetics, etc. Do not store in ordinary residential areas.
2. For your safety and health, please wear a lab coat, disposable gloves and a mask.
3. The experimental results can be affected by many factors. The relevant processing is limited to the product itself and does not involve other compensation.
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