Product Name:

Human Squamous Cell Carcinoma Antigen 1 (SCCA1) ELISA Kit

Cat.#:

KB15310

Regulatory Status:

RUO

Alternative:

SERPINB3; T4-A; Serpin Peptidase Inhibitor,Clade B(ovalbumin),Member 3; Serpin B3

Detection Method:

ELISA

Assay Type:

Sandwich

Detection Range:

78.12-5000pg/mL

Sensitivity:

34.69pg/mL

Specificity:

This kit recognizes Human SCCA1 in samples. No significant cross-reactivity or interference between Human SCCA1 and analogues was observed.

Sample Type:

Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids

| SCCA1

Serpin B3 is a protein that is encoded by the SERPINB3 gene.Enables cysteine-type endopeptidase inhibitor activity; protease binding activity; and virus receptor activity. Involved in several processes, including autocrine signaling; paracrine signaling; and regulation of cellular protein metabolic process. Located in cytoplasmic vesicle; extracellular exosome; and nucleus.SERPINB3 is a Protein Coding gene. Diseases associated with SERPINB3 include Lung Non-Small Cell Carcinoma and Squamous Cell Carcinoma. Among its related pathways are Innate Immune System and Pancreatic cancer subtypes.
 

| Typical data

As the OD values of the standard curve may vary according to the conditions of the actual assay performance (e.g. operator, pipetting technique, wash technique or temperature effects), the operator should establish a standard curve for each test. Typical standard curve and data are provided below for reference only.

  

| Repeatability

Intra-assay Precision (Precision within an assay)：CV% < 10%; Inter-assay Precision (Precision between assays)：CV% < 10%
 

| Recovery

The recovery of Human SCCA1 spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

 

| Linearity

Samples were spiked with high concentrations of Human SCCA1 and diluted with Universal Diluent to produce samples with values within the range of the assay.