Product Name:

Human Syntenin 2 (ST2) ELISA Kit

Cat.#:

KB15409

Regulatory Status:

RUO

Alternative:

SDCBP2; SITAC18; Syndecan Binding Protein 2

Detection Method:

ELISA

Assay Type:

Sandwich

Detection Range:

0.78-50ng/mL

Sensitivity:

0.37ng/mL

Specificity:

This kit recognizes Human ST2 in samples. No significant cross-reactivity or interference between Human ST2 and analogues was observed.

Sample Type:

Serum, plasma, tissue homogenates and other biological fluids

| ST2

Syntenin-2 is a protein that is encoded by the SDCBP2 gene.The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane Proteins, and PDZ-containing Proteins mediate cell signaling and the organization of protein complexes. The encoded protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
 

| Typical data

As the OD values of the standard curve may vary according to the conditions of the actual assay performance (e.g. operator, pipetting technique, wash technique or temperature effects), the operator should establish a standard curve for each test. Typical standard curve and data are provided below for reference only.

  

| Repeatability

Intra-assay Precision (Precision within an assay)：CV% < 10%; Inter-assay Precision (Precision between assays)：CV% < 10%
 

| Recovery

The recovery of Human ST2 spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

 

| Linearity

Samples were spiked with high concentrations of Human ST2 and diluted with Universal Diluent to produce samples with values within the range of the assay.