Human Eomesodermin (EOMES) ELISA Kit KB-E1026H

Regulatory Status:

RUO

Alternative:

TBR2; T-Box Brain 2

Detection Method:

ELISA

Assay Type:

Sandwich

Detection Range:

0.312-20ng/mL

Sensitivity:

0.15ng/mL

Specificity:

This kit recognizes Human EOMES in samples. No significant cross-reactivity or interference between Human EOMES and analogues was observed.

Sample Type:

Tissue homogenates and other biological fluids.

Research Area:

Signal Transduction

| EOMES

Eomesodermin also known as T-box brain protein 2 (Tbr2) is a protein that is encoded by the EOMES gene.The Eomesodermin/Tbr2 gene, EOMES, encodes a member of a conserved protein family that shares a common DNA-binding domain, the T-box.[6] T-box genes encode transcription factors, which control gene expression, involved in the regulation of developmental processes. Eomesodermin/Tbr2 itself controls regulation of radial glia, as well as other related cells.Eomesodermin/Tbr2 has also been found to have a role in immune response, and there exists some loose evidence for its connections in other systems.

| Typical data

As the OD values of the standard curve may vary according to the conditions of the actual assay performance (e.g. operator, pipetting technique, wash technique or temperature effects), the operator should establish a standard curve for each test. Typical standard curve and data are provided below for reference only.

| Repeatability

Intra-assay Precision (Precision within an assay)：CV% < 10%; Inter-assay Precision (Precision between assays)：CV% < 10%

| Recovery

The recovery of Human EOMES spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

| Linearity

Samples were spiked with high concentrations of Human EOMES and diluted with Universal Diluent to produce samples with values within the range of the assay.